
Replacement Diaphragms
Premium Replacement Diaphragms for NovAseptic® Valves
Discover Ultrapharma’s high-quality replacement diaphragms, expertly designed for use with NovAseptic® – MilliporeSigma radial diaphragm valves. Built to withstand the rigors of demanding fluid handling applications, these radial-style diaphragms offer long-lasting performance and trusted reliability.
Our diaphragms are available in a range of sizes and materials, including EPDM and platinum-cured silicone (in both clear and white). Each material is carefully selected and tested to ensure compliance with FDA and USP<88> standards, making them ideal for use in pharmaceutical environments.
For added assurance, every diaphragm is laser-etched with its cure date and lot number, enabling complete batch traceability.
Please note:
NovAseptic® – MilliporeSigma is part of the Life Science business of Merck KGaA, Darmstadt, Germany.
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Ultrapharma Radial Diaphragms
Engineered for Precision and Reliability
Ultrapharma's radial diaphragms are meticulously designed to ensure optimal fluid regulation in critical pharmaceutical and biotechnological processes. Compatible with all OEM NU### series valves, these diaphragms are ideal for applications such as Tank Bottom Outlet Valves and Point of Use valves.
Each diaphragm is laser-engraved with its Lot Number, Date of Manufacture, and NA#, ensuring complete traceability. Manufactured under stringent quality controls, they meet the highest industry standards for safety and performance.
We offer three distinct material options to cater to various operational requirements:

EPDM (NA#/22) – Robust Performance in Demanding Conditions
Crafted from high-quality, peroxide-cured Ethylene Propylene Diene Monomer (CMD-1066), our EPDM diaphragms are designed for durability and resilience. They are particularly suited for environments requiring stringent hygiene and precise process control.
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Applications: Pharmaceutical manufacturing processes, biotechnological applications, and compatible with all OEM NU### series valves.
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Pressure Range: -1 to 6 bar (-14 to 88 PSI).
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Temperature Range: -40°C to SIP at 150°C.
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Compliance: USP<87>, USP<88>, USP<381>, FDA CFR177.2600, and ADIF BSE-TSE free.
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Testing: Validated for up to 500 SIP cycles per ASME BPE Appendix K.

Translucent Platinum Silicone (NA#/26) – Clarity and Consistency
Our translucent platinum-cured silicone diaphragms (CMD-1012) offer excellent flexibility and are ideal for processes where visual inspection is beneficial. They maintain integrity under rigorous sterilization conditions.
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Applications: Pharmaceutical manufacturing processes, biotechnological applications, and compatible with all OEM NU### series valves.
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Pressure Range: -1 to 6 bar (-14 to 88 PSI).
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Temperature Range: -30°C to SIP at 135°C.
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Compliance: USP<87>, USP<88>, FDA CFR177.2600, European Pharmacopoeia 3.1.9, and ADIF BSE-TSE free.
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Testing: Validated for up to 500 SIP cycles per ASME BPE Appendix K.

White Platinum Silicone (NA#/26W) – Enhanced Visibility and Purity
The white variant of our platinum-cured silicone diaphragms (CMD-1065) combines the benefits of silicone with enhanced visibility, aiding in contamination detection and process validation.
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Applications: Pharmaceutical manufacturing processes, biotechnological applications, and compatible with all OEM NU### series valves.
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Pressure Range: -1 to 6 bar (-14 to 88 PSI).
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Temperature Range: -40°C to SIP at 145°C.
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Compliance: USP<87>, USP<88>, USP<381>, FDA CFR177.2600, and ADIF BSE-TSE free.
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Testing: Validated for up to 500 SIP cycles per ASME BPE Appendix K.