Replacement Diaphragms

Premium Replacement Diaphragms

Discover Ultrapharma’s high-quality replacement diaphragms. Built to withstand the rigors of demanding fluid handling applications, these radial-style diaphragms offer long-lasting performance and trusted reliability. Our diaphragms are available in a range of sizes and materials, including EPDM and platinum-cured silicone (in both clear and white). Each material is carefully selected and tested to ensure compliance with FDA and USP<88> standards, making them ideal for use in pharmaceutical environments. For added assurance, every diaphragm is laser-etched with its cure date and lot number, enabling complete batch traceability.

About Replacement Diaphragms

Ensuring product purity and process integrity across the pharmaceutical and biopharmaceutical industries.

Built for long-term performance in critical valve applications

Diaphragms are among the most critical wear components in hygienic process systems. They must withstand repeated flexing, pressure changes and sterilization cycles while maintaining a reliable seal. Ultrapharma’s replacement diaphragms are engineered to deliver consistent performance throughout their service life, helping to maximize valve reliability and reduce unplanned maintenance.

Available in validated EPDM and Platinum Silicone compounds, each diaphragm is manufactured under strict quality controls and laser marked with its cure date and lot number for complete batch traceability. Every material is extensively tested, including validation for repeated SIP cycles, giving pharmaceutical manufacturers confidence in both product consistency and regulatory compliance.

Designed as premium replacement diaphragms for leading valve manufacturers, Ultrapharma products combine proven material performance with comprehensive documentation and traceability, ensuring dependable operation in pharmaceutical and biotechnological applications where product integrity is essential.

Reliable valve performance starts with a trusted diaphragm.

Diaphragms

Ultrapharma Radial-style Diaphragms Engineered for Precision and Reliability

Ultrapharma’s radial-style diaphragms are meticulously designed to ensure optimal fluid regulation in critical pharmaceutical and biotechnological processes. These diaphragms are ideal for applications such as Tank Bottom Outlet Valves and Point of Use valves. Each diaphragm is laser-engraved with its Lot Number & Date of Manufacture, ensuring complete traceability. Manufactured under stringent quality controls, they meet the highest industry standards for safety and performance.

We offer three distinct material options to cater to various operational requirements:

EPDM – Robust Performance in Demanding Conditions

Crafted from high-quality, peroxide-cured Ethylene Propylene Diene Monomer (CMD-1066), our EPDM diaphragms are designed for durability and resilience. They are particularly suited for environments requiring stringent hygiene and precise process control.

  • Applications: Pharmaceutical manufacturing processes & biotechnological applications.
  • Pressure Range: -1 to 6 bar (-14 to 88 PSI).
  • Temperature Range: -40°C to SIP at 150°C.
  • Compliance: USP<87>, USP<88>, USP<381>, FDA CFR177.2600, and ADIF BSE-TSE free.
  • Testing: Validated for up to 500 SIP cycles per ASME BPE Appendix K.

Translucent Platinum Silicone – Clarity and Consistency

Our translucent platinum-cured silicone diaphragms (CMD-1012) offer excellent flexibility and are ideal for processes where visual inspection is beneficial. They maintain integrity under rigorous sterilization conditions.

  • Applications: Pharmaceutical manufacturing processes & biotechnological applications.
  • Pressure Range: -1 to 6 bar (-14 to 88 PSI).
  • Temperature Range: -30°C to SIP at 135°C.
  • Compliance: USP<87>, USP<88>, FDA CFR177.2600, European Pharmacopoeia 3.1.9, and ADIF BSE-TSE free.
  • Testing: Validated for up to 500 SIP cycles per ASME BPE Appendix K.

White Platinum Silicone – Enhanced Visibility and Purity

The white variant of our platinum-cured silicone diaphragms (CMD-1065) combines the benefits of silicone with enhanced visibility, aiding in contamination detection and process validation.

  • Applications: Pharmaceutical manufacturing processes & biotechnological applications.
  • Pressure Range: -1 to 6 bar (-14 to 88 PSI).
  • Temperature Range: -40°C to SIP at 145°C.
  • Compliance: USP<87>, USP<88>, USP<381>, FDA CFR177.2600, and ADIF BSE-TSE free.
  • Testing: Validated for up to 500 SIP cycles per ASME BPE Appendix K.

Ready to Discuss Your Sealing Requirements?

Our technical team is ready to help you select the right solution for your application